Martinus Gijs Ph.D. Physics
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The Microsystems Laboratory 2 of Prof. Martin Gijs has as mission the
development of new microfabrication technologies and to exploit these
for applications of industrial interest. The research is centered
around three themes:
Novel microfabrication technologies
We study the resolution limits of powder blasting micro-erosion as
a process for three-dimensional microstructuring of glass and ceramic
materials. We are developing protein and DNA immobilisation procedures
on solid substrates. We have developed a spin-on-polyimide/Cu
multilayer technology for the realization of high-resolution and
high-quality factor flex-foil circuits. We have established a process
for the replication of three-dimensional and thin film glass
nanostructures by moulding and thermally curing of in-house prepared
spin-on-glass solutions.
Magnetic applications
We have realised three-dimensional millimetre-size power
transformers using a patented ferrite wafer - flex foil batch
fabrication and assembly process. We are working on miniaturised
systems for the handling and magnetic transport of magnetic micro- and
nanoparticles in microfluidic devices.
Microfluidics and Bio-MEMS
We are active in the realisation and use of glass and polymer
microfluidic chips and demonstrated a new pressure pulse sample
injection method for electrophoresis and electrochromatography
applications. We have developed glass and plastic micropumps using
various magnetic actuation and valving principles. We are developing
microsystems for automated cell patch-clamp measurements, with which we
performed experiments on mamalian cells and Xenopus oocytes. We are
developing microfluidic channel- and droplet-based microsystems for the
handling of magnetic beads for biomedical and mixing applications. We
also have realized DNA-chips, where DNA hybridization reactions are
monitored either by fluorescence or impedance measurements.
Career Highlights
Martin A.M. Gijs received his degree in physics in 1981 from the
Katholieke Universiteit Leuven, Belgium and his Ph.D. degree in physics
at the same university in 1986. He joined the Philips Research
Laboratories in Eindhoven, The Netherlands, in 1987. Subsequently, he
has worked there on micro-and nano-fabrication processes of high
critical temperature superconducting Josephson and tunnel junctions,
the microfabrication of microstructures in magnetic multilayers showing
the giant magnetoresistance effect, the design and realisation of
miniaturised motors for hard disk applications and the design and
realisation of planar transformers for miniaturised power applications.
He joined EPFL in 1997. His present interests are in developing
technologies for novel magnetic devices, new microfabrication
technologies for microsystems fabrication in general and the
development and use of microsystems technologies for microfluidic and
biomedical applications in particular.
Important Articles
A PMMA valveless micropump using electromagnetic actuation, C. Yamahata, C. Lotto, E. El-Assaf, and M.A.M. Gijs, Microfluidics and Nanofluidics 1, 197-207 (2005)
Precision poly-(dimethyl siloxane) masking technology for high-resolution powder blasting, A.-G. Pawlowski, A. Sayah, and M. A. M. Gijs, J. Microelectromechanical Systems 14, 619-623 (2005)
Pumping of mammalian cells with a nozzle-diffuser micropump, C. Yamahata, C. Vandevyver, F. Lacharme, P. Izewska, H. Vogel, R. Freitag, and M.A.M. Gijs, Lab on a Chip 5, 1083-1088 (2005)
Manipulation of self-assembled structures of magnetic beads for microfluidic mixing and assaying, A. Rida and M.A.M. Gijs, Analytical Chemistry 76, 6239 (2004)
Magnetic bead handling on-chip: new opportunities for analytical applications (review), M.A.M. Gijs, Microfluidics and Nanofluidics 1, 22-40 (2004)
Dynamics of magnetically retained supraparticle structures in a liquid flow, A. Rida and M.A.M. Gijs, Appl. Phys. Lett. 85, 4986-4988 (2004)
Reactive oxide micro molding of diffractive optical elements in glass and transparent ceramics,
V.K. Parashar, A. Sayah, and M.A.M. Gijs, Proceed. of the 17th IEEE
International Conference on Micro Electro Mechanical Systems,
Maastricht, The Netherlands, January 25-29, pp. 458-461 (2004)
Enhanced sensitivity detection of protein immobilization by fluorescent interference on oxidized silicon,
J.-N. Volle, G. Chambon, A. Sayah, C. Reymond, N. Fasel, and M.A.M.
Gijs, Biosensors and Bioelectronics 19, pp. 457-464 (2003)
Pressure pulse injection: a powerful alternative to electrokinetic sample loading in electrophoresis microchips, Solignac, D. and M. A. M. Gijs , Analytical Chemistry 75, 1652-1657 (2003)
Long-range transport of magnetic microbeads using simple planar coils placed in a uniform magnetostatic field, A. Rida, V. Fernandez, and M.A.M. Gijs
, Appl. Phys. Lett. 83, 2396-2398 (2003)
Realization of hollow SiO2 micronozzles for electrical measurements on living cells, T. Lehnert, M.A.M Gijs, R. Netzer, and U. Bischoff, Appl. Phys. Lett. 81, 5063-5065 (2002)
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