Hiroyuki Isobe Ph.D.

Isobe, Hiroyuki
Position Department / Business Unit
Department of Chemistry
Institution Disciplines
The University of Tokyo Chemistry
City State / Provence
Country Website
Japan link

Dr. Isobe’s thesis work describes design and synthesis of functional DNA binding molecules with fullerene scaffold. The binding to and recognition of DNA by synthetic organic compounds is important and challenging subjects, and the present study shed the light on the new synthetic route to DNA binding molecules. Development of symmetry-defined multiple addition reactions to [60]fullerene has led to the rational design of functional DNA binding molecule.

Work on his thesis, “Design and Synthesis of DNA Binding Organofullerene" started with studies on the organofunctionalization of fullerene, specifically on reactivities of fullerene toward vinylcarbene species and silyl ketene acetals. The work on the thermal and photochemical reactions with fullerene gave an important information of inherent reactivity of fullerenes. With such fundamental method in hand, I started to investigate a new route to the structurally unique organofullerenes.


1994 B. S. in Chemistry (Tokyo Institute of Technology); 1996 M. S. in Chemistry (Tokyo Institute of Technology); 1999 Ph. D. in Chemistry (The University of Tokyo)

Career Highlights

Research and Professional Experience:
1996-1998, JSPS Fellow
1996 June-August, Visiting Student in Princeton University (Prof. Daniel Kahne)
1998-2004, Assistant Professor, Department of Chemistry, The University of Tokyo
2003-present, PRESTO, JST
2004-present, Associate Professor, Department of Chemistry, The University of Tokyo


2000 The 1st IUPAC Prize for Young Chemists
2001 The 1st Young Scientist's Research Award in Natural Product Chemistry
2004 The Chemical Society of Japan Award for Young Chemists
2005 The 1st Osawa Award of Fullerene Nanotube Research Association

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