Michael Pycraft Hughes Ph.D.

Hughes, Michael Pycraft
Position Department / Business Unit
Lecturer Biomedical Engineering
Institution Disciplines
University of Surrey Engineering
City State / Provence
Surrey
Country Website
United Kingdom
Fax

Dr. Michael Hughes is a Reader in Biomedical Engineering at the University of Surrey. He is currently developing new tools for analysis of carbon nanotubes and other nanoparticles using dielectrophoresis, and creating a spin-out venture using the technology to study and separate particles ranging in size from cells to nanoparticles.

Dr. Hughes has been directly involved in research into dielectrophoretic manipulation of particles for nearly 10 years, and has published over 60 journal and conference papers on the subject.

He has thus far been awarded over $1M in grant funding, approximately 80% of which has been as either principal or sole investigator. Much of this has been to fund research into the dielectrophoretic manipulation of particles, including a research programme with DSTL Porton Down on the enhancement of biosensors for bacterial and viral detection, award of a feasibility study into the manipulation and separation of nanotubes from EPSRC, and the development of novel electrode structures for cell characterisation; That work has recently been patented, as has his work on 3D dielectrophoretic separation devices.

Career Highlights

He was appointed in 1999 as lecturer in microengineering in the Centre for Biomedical Engineering at the University of Surrey, forming part of the new School of Engineering.

Prior to his appointment at Surrey, Dr Hughes was a temporary lecturer in the University of Glasgow, following a 3-year, BBSRC-funded postdoctoral position in the Bioelectronic Research Centre of Glasgow, on the use of dielectrophoresis to investigate the biophysical properties of bacteria and viruses in vitro. During this period, he was involved in pioneering work in the dielectrophoretic manipulation of virus particles for biophysical study and virus separation.

His PhD research (1992-5), entitled “Electrokinetics of particles: computer-aided studies”, concerned the simulation of the electrostatic interactions between cells and electric fields, conducted at the University of Wales Bangor and the MD Anderson Cancer Research Center (Houston, USA), where he was involved in the simulation of dielectrophoretic effects in the aid of separation of cancer cells from blood. He is a Chartered Physicist, a member of the Institute of Physics and the Institute of Nanotechnology, and Member of the Institute of Electronic and Electrical Engineers.

Awards

He has presented invited lectures on the subject of dielectrophoretic manipulation of nanoparticles at
  • Trends in Nanocomputing conference (Madras, India, 2001),
  • The CECAM Workshop on Molecular Motors (Lyon, France, 2002), The American Physical Society’s annual meeting in Austin, (USA) in 2003, and
  • The Institute of Physics Biodielectrics meeting (Leicester, England, 2006)

Books

He has written a textbook a book on dielectrophoretic manipulation of nanometre-scale particles
and is also a contributed chapters to the

Important Articles

Dr. Hughes recently published a review paper on dielectrophoretic separation for a special issue of the journal Electrophoresis. He also published a number of papers on the physics of the electrical double-layer surrounding colloidal particles, as observed by dielectrophoretic manipulation, and continues to pursue this research.

He is also a Senior Editor of the IEEE journal, “IEEE Transactions on Nanobioscience”.

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