Nanoparticulate Drug Delivery Systems
Michel Deleers UCB Pharma
Yashwant Pathak Sullivan Unversity
Deepak Thassu Holopack International Corporation
Since the advent of analytical techniques and capabilities to measure particle sizes in nanometer ranges, there has been tremendous interest in the use of nanoparticles for more efficient methods of drug delivery. This expertly written guide addresses the scientific methodologies, formulation, processing, applications, recent trends, and emerging technologies in the research of nanoparticulate drug delivery systems (NPDDS). It extensively covers applications of NPDDS, including lipid nanoparticles for dermal applications, nanocarriers for the treatment of restenosis, ocular, central nervous system, and gastrointestinal applications, and use as an adjuvant for vaccine development.
Table of ContentsNanoparticulate Drug Delivery Systems: An Overview. Nanosuspensions for Parenteral Delivery. Nanoparticles Prepared Using Natural and Synthetic Polymers. Nanofiber-based Drug Delivery. Drug Nanocrystals: The Universal Formulation Approach for Poorly Soluble Drugs. Lipid Based Nanoparticulate Drug Delivery Systems. Nanoengineering of Drug Delivery Systems. Aerosol Flow Reactor Method for the Synthesis of Multi Component Drug Nano and Micron Particles. Supercooled Smectic Nanoparticles. Biological and Engineering Considerations for Developing Tumor Targeting Metallic Nanoparticles Drug Delivery Systems. Biological Requirements for Nano Therapeutic Applications. Role of Nanobiotechnology in the Development of Nanomedicine. Pharmaceutical Applications of Nanoparticulate Drug Delivery Systems. Lipid Nanoparticles (SLN and NLC) in Cosmetic, Dermal and Transdermal Applications. Nano Carriers of Drugs and Genes for the Treatment of Restenosis. Ocular Applications. Nanoparticulate Systems for CNS Drug Delivery. Nanoparticles for Gene Delivery: Formulation Characteristics. GI Applications. Nanoparticles as Adjuvants for Vaccination. Transdermal Applications of Nanoparticulate Delivery Systems.
ContributorsContributor Cohen-Sela, Einat, The Hebrew University Contributor Shim, Jongwon, Amorepacific Corporation Contributor Chiang, Joseph, State Univ of New York-Oneonta Contributor Espuelas, Socorro, Departmento de Farmacia Y Contributor Burke, Matthew D., Glaxo Smith Kline Contributor Ludwig, Annick, University of Antwerp Contributor Paciotti, Giulio F., CytImmune Sciences, Inc. Contributor Jain, K.K., Contributor Olivier, Jean-Christophe, Faculte de Medecine et de Pharmacie Contributor Rabinow, Barrett E., Baxter Healthcare Corporation, Round Lake, MI, USA Contributor Souto, Eliana B., Contributor Golomb, Gershon, Hebrew University, Jerusalem, Israel Contributor Kauppinen, Esko I., Helsinki Univ. of Technology Contributor Labhasetwar, Vinod, University of Nebraska, Omaha, Nebraska, USA Contributor Lee, Robert J., The Ohio State University, Columbus, USA Contributor Shastri, V. Prasad, Vanderbilt University Contributor Bunjes, Heike, Universitat Braunschweig Editor 1 Thassu, Deepak, Holopack International Group, Columbia, South Carolina, USA Editor 2 Deleers, Michel, UCB Pharma, Chemin du Foriest, Braine L'Alleud, Belgium Editor 3 Pathak, Yashwant, Sullivan University, Louisville, Kentucky, USA
by siebo — last modified September 21, 2009 - 09:18