Nanotechnology in Therapeutics: Current Technology and Applications
DescriptionNanotechnology is a multidisciplinary field covering a large and diverse array of devices and materials in nanometer scale, derived from engineering, physics, chemistry and biology. The field of applied nanotechnology in medicine is growing fast and the application of nanotechnology to therapeutics has led to advances in drug delivery, biomaterials, biomedical devices, intelligent processes and in many other areas of medicine and applied biomedical sciences. The authors of this volume describe and discuss current technology and the applications of nanoparticles and nanostructures in various aspects of therapeutics and drug delivery. The chapters are completely up-to-date and are written by some of the leading scientists in the field. Topics covered include chronobiology, chronopharmacology and chronotherapeutics, polymeric gene delivery vectors, biohybrid materials, biomimetic systems, hydrogel nanocomposites, star polymers and dendrimers, ionic nanoparticulate systems, nanospheres and nanoparticles. Entire chapters are devoted to specific applications of nanotechnology such as cancer therapy, bone disorders, and diabetes. Table of ContentsSection A: Intelligent Therapeutics and Responsive Delivery Systems for Improved Absorption and Delivery1. Concepts of Medical Chronobiology, Chronopharmacology and Chronotherapeutics as the Basis for Applications of Drug Delivery Technology 2. Feedback Control in Drug Delivery 3. Advances in Drug Delivery Technologies for Nanoparticulates 4. Synthetic Ligand-Receptor Interactions in Delivery Systems 5. Nanoscale Analysis of Mucus-Carrier Interactions for Improved Drug Absorption 6. Polymeric Gene Delivery Vectors Section B: Therapeutic Micro- and Nanodevices 1. Biohybrid Materials for Therapeutic Devices Section C: Nanostructured Therapeutic Materials 1. Biomimetic Systems: A Synergy of Scientific and Engineering Approaches 2. Hydrogel Nanocomposites for Intelligent Therapeutics 3. Nanotechnology for Treating Bone Disorders 4. Nanotechnology and Cancer Therapy 5. Nanostructured Scaffolds for Tissue Engineering Section D: Nanoparticulate Systems in Intelligent Therapy 1. Star Polymers and Dendrimers in Nanotechnology and Drug Delivery 2. Ionic Nanoparticulate Systems for Drug Delivery 3. Nanospheres of Intelligent Networks for Biomedical and Drug Delivery Applications 4. Shell Crosslinked Nanoparticles: A Progress Report of Their Design for Drug Delivery 5. Nanoparticulate Structures in Diabetes Treatment ContributorsEditor 1 Peppas; Nicholas University of Texas, USA Editor 2 Hilt; J. Zach University of Kentucky, USA Editor 3 Thomas, J. Brock University of Texas, USA Contributor (Other) Donini; Christina Department of Chemical Engineering, The University of Texas at Austin, Austin, TX Contributor (Other) Benoit; Danielle S.W. Department of Chemical and Biological Engineering, University of Colorado, Boulder, CO Contributor (Other) Robinson; Daphne N. Department of Chemical Engineering, The University of Texas at Austin, Austin, TX Contributor (Other) Henthorn; David B. Department of Chemical and Biological Engineering, University of Missouri-Rolla, Rolla, MO Contributor (Other) Moschou; Elizabeth A. Department of Chemistry, University of Kentucky, Lexington KY Contributor (Other) Balasundaram; Ganesan Division of Engineering, Brown University, Providence, RI Contributor(Other) Park; Grace Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN Contributor (Other) Kang; Han Chang Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, Salt Lake City, Utah Contributor (Other) Hilt; Zach J. Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY Contributor (Other) Blanchette; James O. Department of Chemical Engineering, The University of Texas at Austin, Austin, TX Contributor (Other) Florian Jr.; Jeffry A. Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA Contributor (Other) Xu; Jinqi Washington University in Saint Louis, Center for Materials Innovation and Department of Chemistry, Saint Louis, MO Contributor(Other) Wooley; Karen L. Washington University in Saint Louis, Center for Materials Innovation and Department of Chemistry, Saint Louis, MO Contributor (Other) Overhoff; Kirk A. College of Pharmacy, The University of Texas at Austin, Austin, TX Contributor (Other) Anseth; Kristi S. Department of Chemical and Biological Engineering, University of Colorado, Boulder CO Contributor (Other) Bachas; Leonidas G. Department of Chemistry, University of Kentucky, Lexington KY Contributor (Other) Byrne; Mark E. Biomimetic and Biohybrid Materials, Biomedical Devices, and Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, Alabama, USA Contributor (Other) Lee; Minhyung Department of Bioengineering, College of Engineering, Hanyang University, Korea Contributor (Other) Bures; Petr Department of Chemical Engineering, The University of Texas at Austin, Austin, TX Contributor (Other) Frimpong; Reynolds A. Department of Chemical and Materials Engineering, University of Kentucky, Lexington, KY Contributor (Other) Williams III; Robert O. College of Pharmacy, The University of Texas at Austin, Austin, TX Contributor (Other) Parker; Robert S. Department of Chemical and Petroleum Engineering, University of Pittsburgh, Pittsburgh, PA Contributor (Other) Venkatesh; Siddarth Biomimetic and Biohybrid Materials, Biomedical Devices, and Drug Delivery Laboratories, Department of Chemical Engineering, Auburn University, Auburn, Alabama Contributor (Other) Seidlits; Stephanie Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX Contributor (Other) Daunert; Sylvia Department of Chemistry, University of Kentucky, Lexington KY Contributor (Other) Webster; Thomas J. Division of Engineering, Brown University, Providence, RI Contributor (Other) Sun; Guorong Washington University in Saint Louis, Center for Materials Innovation and Department of Chemistry, Saint Louis, MO Contributor (Other) Li; Yali Washington University in Saint Louis, Center for Materials Innovation and Department of Chemistry, Saint Louis, MO Contributor (Other) Huang; Yanbin Department of Chemical Engineering, The University of Texas at Austin, Austin, TX Contributor (Other) Bae; You Han Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, Salt Lake City, Utah Contributor (Other) Zheng, Youyo Department of Chemical and Biological Engineering, University of Missouri-Rolla, Rolla, MO |
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