Nanotechnology for Cancer Therapy

 Nanotechnology for Cancer Therapy
Publication Type List Price
Book $ 189.95 / £ 100
Publication Date Imprint
12/19/06 CRC
Disciplines ISBN
Nanomedicine 9780849371943
Number of Pages Buy with discount
840 buy
   
view list

Description

Encouraging communication between clinical investigators and nanoscientists, Nanotechnology for Cancer Therapy focuses specifically on effective and promising nanoscience and nanotechnology strategies for imaging and treating cancer. Among the various approaches considered, nanotechnology offers the best promise for the targeted delivery of drugs and genes to a tumor site and for alleviating side effects of chemotherapeutic agents. Renowned industrial and academic researchers describe the advantages of nanoparticles as sensing, delivery, image enhancement agents for cancer treatments, and various types of useful nanoparticles such as polymeric nanoparticles and dendrimers.

Table of Contents

SECTION 1 NANOTECHNOLOGY AND CANCER
Introduction and Rationale for Nanotechnology in Cancer Therapy; Fredika M. Robertson and Mauro Ferrari
Passive Targeting of Solid Tumors: Pathophysiological Principles and Physicochemical Aspects of Delivery Systems; S. M. Moghimi
Active Targeting Strategies in Cancer with a Focus on Potential Nanotechnology Applications; Randall J. Mrsny
Pharmacokinetics of Nanocarrier-Mediated Drug and Gene Delivery; Yuriko Higuchi, Shigeru Kawakami, and Mitsuru Hashida
Multifunctional Nanoparticles for Cancer Therapy; Todd J. Harris, Geoffrey von Maltzahn, and Sangeeta N. Bhatia
Neutron Capture Therapy of Cancer: Nanoparticles and High Molecular Weight Boron Delivery Agents; Gong Wu, Rolf F. Barth, Weilian Yang, Robert J. Lee, Werner Tjarks, Marina V. Backer, and Joseph M. Backer
Preclinical Characterization of Engineered Nanoparticles Intended for Cancer Therapeutics; Anil K. Patri, Marina A. Dobrovolskaia, Stephan T. Stern, and Scott E. McNeil
Nanotechnology: Regulatory Perspective for Drug Development in Cancer Therapeutics; N. Sadrieh and T. J. Miller

SECTION 2 POLYMER CONJUGATES
Polymeric Conjugates for Angiogenesis Targeted Tumor Imaging and Therapy; Amitava Mitra, Anjan Nan, Bruce R. Line, and Hamidreza Ghandehari
Poly (L-Glutamic Acid): Efficient Carrier of Cancer Therapeutics and Diagnostics; Guodong Zhang, Edward F. Jackson, Sidney Wallace, and Chun Li
Noninvasive Visualization of In Vivo Drug Delivery of Paramagnetic Polymer Conjugates with MRI; Zheng-Rong Lu, Yanli Wang, Furong Ye, Anagha Vaidya, and Eun-Kee Jeong

SECTION 3 POLYMERIC NANOPARTICLES
Polymeric Nanoparticles for Tumor-Targeted Drug Delivery; Tania Betancourt, Amber Doiron, and Lisa Brannon-Peppas
Long-Circulating Polymeric Nanoparticles for Drug and Gene Delivery to Tumors; Sushma Kommareddy, Dinesh B. Shenoy, and Mansoor M. Amiji
Biodegradable PLGA/PLA Nanoparticles for Anticancer Therapy; Sanjeeb K. Sahoo and Vinod Labhasetwar
Poly (alkyl cyanoacrylate) Nanoparticles for Delivery of Anticancer Drugs; R. S. R. Murthy and L. Harivardhan Reddy
Aptamers and Cancer Nanotechnology; Omid C. Farokhzad, Sangyong Jon, and Robert Langer

SECTION 4 POLYMERIC MICELLES
Polymeric Micelles for Formulation of Anticancer Drugs; Helen Lee, Patrick Lim Soo, Jubo Liu, Maok Butler, and Christine Allen
PEO-Modified Poly (L-Amino Acid) Micelles for Drug Delivery; Afsaneh Lavasanifar, Xiuo-Bing Xiong, and Hamidreza Montazeri Aliabadi
Hydrotropic Polymer Micelles for Cancer Therapeutics; Sang Cheon Lee, Kang Moo Huh, Tooru Ooy, and Kinam Park
Tumor-Targeted Delivery of Sparingly-Soluble Anti-Cancer Drugs with Polymeric Lipid-Core Immunomicelles; Vladimir P. Torchilin
Combined Cancer Therapy by Micellar-Encapsulated Drug and Ultrasound; Natalya Rapoport
Polymeric Micelles Targeting Tumor pH3; Eun Seong Lee and You Han Bae
cRGD-Encoded, MRI-Visible Polymeric Micelles for Tumor-Targeted Drug Delivery; Jinming Gao, Norased Nasongkla, and Chalermchai Khemtong
Targeted Antisense Oligonucleotide Micellar Delivery Systems; Ji Hoon Jeong, Sun Hwa Kim, and Tae Gwan Park

SECTION 5 DENDRITIC NANOCARRIERS
Dendrimers as Drug and Gene Delivery Systems; Tae-Il Kim and Jong-Sang Park
Dendritic Nanostructures for Cancer Therapy; Ashootosh V. Ambade, Elamprakash N. Savariar, and S. Thai Thayumanavan
PEGylated Dendritic Nanoparticulate Carriers of Anti-Cancer Drug; D. Bhadra, S. Bhadra, and N. K. Jain
Dendrimer Nanocomposites for Cancer Therapy; Lajos P. Balogh and Mohamed K. Khan

SECTION 6 LIPOSOMES
Applications of Liposomal Drug Delivery Systems to Cancer Therapy; Alberto A. Gabizon
Positively-Charged Liposomes for Targeting Tumor Vasculature; Robert B. Campbell
Cell Penetrating Peptide (CPP)-Modified Liposomal Nanocarriers for Intracellular Drug and Gene Delivery; Vladimir P. Torchilin
RGD-Modified Liposomes for Tumor Targeting; S. P. Vyas
Folate Receptor-Targeted Liposomes for Cancer Therapy; Xiaobin B. Zhao, Natarajan Muthusamy, John C. Byrd, and Robert J. Lee
Nanoscale Drug Delivery Vehicles for Solid Tumors: A New Paradigm for Localized Drug Delivery Using Temperature Sensitive Liposomes; David Needham and Ana Ponce

SECTION 7 OTHER LIPID NANOSTRUCTURES
Nanoemulsions Formulations for Tumor-Targeted Delivery; Sandip B. Tiwari and Mansoor M. Amiji
Solid Lipid Nanoparticles for Antitumor Drug Delivery; Ho Lun Wong, Yongqiang Li, Reina Bendayan, Mike Andrew Rauth, and Xiao Yu Wu
Lipoprotein Nanoparticles as Delivery Vehicles for Anti-Cancer Agents; Andras G. Lacko, Maya Nair, and Watter J. McConathy
DQAsomes as Mitochondria-Targeted Nano-Carriers for Anticancer Drugs; Shing-Ming Cheng, Sarathi V. Boddapati, Gerard G. M. D'Souza, and Volkmar Weissig

Contributors

by siebo last modified April 17, 2008 - 08:27
Document Actions

Features

  • Focuses exclusively on the application of nanoscience and nanotechnology to the various strategies in cancer prevention, diagnosis, and treatment
  • Facilitates discussion between researchers involved in cancer therapy and nanoscientists and engineers
  • Describes the advantages of nanoparticles as sensing, delivery, and image enhancement agents for cancer therapeutics
  • Covers various nano-platforms, including polymeric conjugates, micelles, dendrimers, and nanoassemblies
  • Examines micellar delivery systems currently undergoing clinical trials across the globe
  • Reviews



    Nanotechnology may be our best hope for overcoming many of the barriers faced by today's drugs in the battle against cancer. The combined creative forces of engineering, chemistry, physics, and biology will beget new and hopefully transformative options to old, intractable problems.
    -- Piotr Grodzinski, National Cancer Institute, from the Foreword