Micro and Nano Techniques for the Handling of Biological Samples

Jaime Castillo DTU Nanotech, Technical University of Denmark
Winnie Svendsen Technical University of Denmark
Maria Dimaki Technical University of Denmark
Publication Type List Price
Reference $129.95 / £82
Publication Date Imprint
08/24/2011 CRC Press
Disciplines ISBN
Nanobiotechnology 9781439827437
Number of Pages Buy with discount
255 buy
   

Description

Several micro- and nanomanipulation techniques have emerged in recent decades thanks to advances in micro- and nanofabrication. For instance, the atomic force microscope (AFM) uses a nano-sized tip to image, push, pull, cut, and indent biological material in air, liquid, or vacuum. Using micro- and nanofabrication techniques, scientists can make manipulation tools, such as microgrippers and nanotweezers, on the same length scale as the biological samples. Micro and Nano Techniques for the Handling of Biological Samples reviews the different techniques available to manipulate and integrate biological materials in a controlled manner, either by sliding them along a surface (2-D manipulation), or by gripping and moving them to a new position (3-D manipulation). The advantages and drawbacks are mentioned together with examples that reflect the state-of-the-art in manipulation techniques for biological samples. Thanks to the advances in micro- and nanomanipulation techniques, the integration of biomaterials with physical transducers has been possible, giving rise to new and highly sensitive biosensing devices. Although great progress has been made, challenges are still present. To understand the complex interactions between and inside biological samples, scientists will always be working on improving technologies to manipulate, transport, sort, and integrate samples in different environments. Balanced between simplicity for the beginner and hardcore theory for the more advanced readers, this book is the ideal launching point for sharpening the scientific tools required to address these challenges.

by gilbertb last modified July 31, 2011 - 16:59
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Features

- Provides a comprehensive description of various techniques currently available for manipulating biological samples - Evaluates the advantages and limitations of each technique, helping readers to determine the appropriate tool for their needs and to understand how the manipulation tools work - Illustrates the use of the techniques in research and analytical laboratories