Virus Nanoparticles: Adsorption and Organization on Substrates


Jiyu Fang Advanced Materials Processing and Analysis Center, University of Central Florida

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Virus particles are supramolecular structures containing a nucleic acid [either deoxyribonucleic acid (DNA) or ribonucleic acid (RNA)] core surrounded by a protein layer, known as the capsid. They are important entities in biological systems and useful templates for the synthesis of inorganic nanocrystals. Recently, studies regarding the interfacial behavior of virus particles have begun to emerge from the understanding of two-dimensional (2-D) protein crystallization, the immobilization for studying their structures with atomic force microscopy (AFM) and the preparation of scaffolds for assembling mesoscale materials. The adsorption and organization of virus particles on surfaces are the topic of this article.