Metal Nanoparticles Modified with Molecular Receptors


Jian Liu Department of Chemistry, Michigan Technological University

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Presently, monolayer-protected metal nanoparticles (MPNPs) are the subjects of some exciting and very active interdisciplinary research because of the rapid development of preparation methods using organic thiols as stabilizers. The organic monolayer not only protects the particles from agglomeration, but also furnishes a scaffold for the construction of different functional entities on their surfaces leading to a broad range of interesting applications. Among these studies, the attachment of molecular receptors capable of engaging in well-defined host–guest interactions is receiving considerable attention. This article summarizes recent advancements in the development and applications of artificial receptor-modified metal nanoparticles. The research work on metal nanoparticles modified with biological species, such as DNA, was reviewed recently; thus this topic will not be included here.